MASS SPECTROMETRY RESOURCE

Theory Section

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In this section of the web site you will find a detailed description of the basic and advanced theories of mass spectrometry. This will cover the various common place methods of sample ionisation and mass measurement as well as details of ion detection, hyphenated techniques, multiple sector/multistage mass analysis (tandem and sequential mass spectrometry) and some basic ideas about ion fragmentation chemistry. More details can also be found on the relevant research pages.

Ions & Ionisation Methods	Mass Measurement & Ion Detection
Electron Ionisation (EI) & Chemical Ionisation (CI)	Magnetic Sector
Electrospray Ionisation (ESI)	Time-of-Flight (TOF-MS)
Atmospheric Pressure Chemical Ionisation (APCI)	Quadrupole & Triple Quadrupole (QQQ)
Nanospray Ionisation	Quadrupole Ion Trap (QIT)
Matrix-assisted Laser Desorption/Ionisation (MALDI)	Fourier-Transform Ion Cyclotron Resonance (FT-ICR)
Fast Atom Bombardment (FAB) & Liquid Secondary Ion Mass Spectrometry (LSIMS)	Methods of Ion Detection
Types of Ions Formed in Mass Spectrometry

Hyphenated Techniques	Fragmentation Studies
Liquid Chromatography - Mass Spectrometry (LC-MS)	Collision Induced Dissociation (CID)
Gas Chromatography - Mass Spectrometry (GC-MS)	Tandem Mass Spectrometry (MS/MS)
Pyroloysis-GC-Mass Spectrometry (Py-GC-MS)	Multistage (Sequential) Tandem Mass Spectrometry (MSn)
GC Combustion Isotope Ratio Mass Spectrometry (GC-C-IRMS)	An Introduction to Fragmentation Theory
	Other Methods of Ion Fragmentation in MS